Is 4 OHT possible in Nasal Delivery?

1Fast400 Forums > Hormone/Prohormones


Posted by: Cycling Man Feb 13 2004, 01:11 AM
[PRODUCT]459[/PRODUCT] Is 4 OHT possible in Nasal Delivery? Is it soluble in saline and HPCBD?

Posted by: Loki Feb 13 2004, 08:27 AM
Yes it is. (My response to both Qs)

But--if I may ask--in regards to the latter-- why? 4-OHT really has so significant, immediate psychological effects (contrast that with a DHT-PH like 5AA) that would make it a good pre-workout stimulant or mental fatigue-fighter. Similarly, a cyclodextrin-complexed 4-OHT suspension would never be able to deliver enough 4-OHT to ellicit a consistent, tangible anabolic effect unless you doses it 8-10+ time/day, which seems like a bit of a waste to me...

Posted by: shpongled Feb 14 2004, 04:56 AM
QUOTE (Loki @ Feb 13 2004, 08:27 AM)
Yes it is. (My response to both Qs)

But--if I may ask--in regards to the latter-- why? 4-OHT really has so significant, immediate psychological effects (contrast that with a DHT-PH like 5AA) that would make it a good pre-workout stimulant or mental fatigue-fighter. Similarly, a cyclodextrin-complexed 4-OHT suspension would never be able to deliver enough 4-OHT to ellicit a consistent, tangible anabolic effect unless you doses it 8-10+ time/day, which seems like a bit of a waste to me...

Yeah, and even at that dose I doubt that you would notice anything - considering that (on paper) it is only 10% as anabolic as 1-test.

Posted by: robert20981 May 22 2005, 04:16 PM
How pure is this stuff ?
I wonder if I can make an injectable out of it,if I add some BA.

Would BA be a possible component in cyclo without messing it up?

On the other hand a Formestane-Cyclo and TNE-Cyclo sublingual would be sufficient,but Formestane and Cyclo as an inject would be very interesting.

Rob

Posted by: ecko3003 May 22 2005, 10:50 PM
dont try it too many boogers

Posted by: sdf42450 May 22 2005, 10:57 PM
QUOTE (robert20981 @ May 22 2005, 03:16 PM)
How pure is this stuff ?
I wonder if I can make an injectable out of it,if I add some BA.

Would BA be a possible component in cyclo without messing it up?

On the other hand a Formestane-Cyclo and TNE-Cyclo sublingual would be sufficient,but Formestane and Cyclo as an inject would be very interesting.

Rob

goodluck with it in BA... that stuff makes some nice pointy crystals in depot, have fun

*great stuff though*

Posted by: Tom24989 Jun 1 2005, 01:05 PM
Anyone know how many grams of cyclodextrins are used with each gram of base hormone?

Posted by: AgnosticFront Jun 1 2005, 01:08 PM
10:1

Posted by: robert20981 Jun 25 2005, 10:01 AM
QUOTE (AgnosticFront @ Jun 1 2005, 01:08 PM)
10:1

Itīs more like 9:1 but I think even less.
Iīve had problems with undissolved cyclo in saline at a 9:1 ratio.

Therfor I will dissolve the cyclo first until it has saturated the salin and then add the base..whatever to the mix,so maybe this time ,less undissolved particles will occure. ohmy.gif

Posted by: AgnosticFront Jun 25 2005, 12:56 PM
QUOTE
Method1
For the first method we will formulate it for a total of 2g of steroid.
Dissolve 18g of HPBCD in 80ml saline in a beaker on a stir plate. Once this is dissolved, slowly add the 2g of steroid over about 5 minutes. Let this stir overnight. Filter out any insoluble particles. This provides a 25mg/ml solution.

Method 2
For the second method, we will formulate it for 1g of steroid.
Triturate (mix in a mortar with a pestle) 9g HPBCD with 1g steroid. Place this in a high humidity environment for 2-4 days. I have used a covered fish tank with water in the bottom, but anything that can create a humid environment will work. A syrup will form, and this is dissolved in 40ml saline and you have a 25mg/ml solution.

Method 3
For the third method, we will formulate for 4g of steroid.
Triturate 36g of HPBCD with 4g steroid. Let this sit at normal room temperature and humidity for a week. Complexation will occur, but takes time with this process Dissolve the powder in 160ml saline. This again makes a 25mg/ml solution.


looks like your right... 9:1