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> RE Transport Matrix, Absorption Efficiency
Posted: Jun 29 2005, 10:08 PM
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Transport Matrix
What is approximate aborption efficiency ratio of this transport matrix? For example AndroGel has about 10% absorption through the skin and into the bloodstream. 5 grams of AndroGel, 1% strength testosterone, means that it has 50mg of testosterone. But only 10% of that testosterone - or 5 mg - makes it through the skin barrier and into the bloodstream.

My question is what is the efficiency ratio for this product? Some of the home brews have indicated an efficiency rate of 40%.

If that was the case, wouldn't someone on TRT be better off to buy the smaller 2.5 grams packets of AndroGel and use a transport matrix (or homebrew) to transport the testosterone across the skin barrier and into the bloodstream? At a 40% efficiency ratio that would mean a 2.5 gram packet of AndroGel would deliver 10 mg of testosterone (or pretty much an ideal amount).

OR......

Instead of simply being a more efficient transport methodology, would that concept defeat the purpose of delivering a metered dteady dose during the day? The AndroGel formulation - while pretty crappy at how much it delivers across the skin barrier - is apparently formulated so that the testosterone is slowly leached into the bloodstream over the course of the day. Would getting more across faster simply end up with an early spike and then a rapid drop off later (I believe that testosterone has a half life of something like 100 - 120 minutes)?

All just speaking theoretically of course.....

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Posted: Jun 29 2005, 10:42 PM
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About 30%, assuming that u are not as hairy as a yeti and that u are not covered in oil, grease and paint like us mexicans.
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