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L -Tryptophan, it's available |  |
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Namaste!

Group: Advanced Members
Posts: 1142
Member No.: 6166
Joined: 25-July 03

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 Guys...after reading the FDA statement on that site I decided to check and see iff I could find L-T anywhere else. Here is what I found on one site that sells it in both capsule and powder form: USP Pharmaceutical Grade 99.6% PURE L Tryptophan NO Fillers, NO Pouring Agents, Nothing Added ! YES..Vegetarian Capsules, YES..All Vegan Source ! **This is NOT 5HTP (which is less effective in at least 90% of patients) and costs much less to manufacture. This product as shown by our Certificate of Analysis..is the highest grade available in the world..over 99% PURE. That is why we're the first choice for Dr's and Pharmacies and now...you. Here is the website, if you want to check it out. http://www.beautynhealth.com/tryptophan/index.htmI think I will definitely give it a shot. I have suffered from (social) anxiety disorders most of my life and have dealt with pretty severe depression twice...not to mention minor depressive bouts. Good Luck!
So the question is not: Why start off on such a path? You have already started off. You did so with the first beat of your heart. The question is: Do I wish to walk this path consciously or unconsciously? With awareness or lack of awareness? As the cause of my experience, or at the effect of it?
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none

Group: Members
Posts: 11
Member No.: 29654
Joined: 25-May 04

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 From what I remember a bad batch from china allegedly caused several deaths. I took it for years with no negative effects. Had a great calming effect and gave a STRONG sense of well being(you could really feel a difference, not a placebo effect) and was VERY VERY cheap to buy. All the health food stores were offering full refunds for any products that contained any tryptophan, it was pretty stupid they were acting like it was poison. I used to take Solgar brand V tabs(i think that was the name) multi-vitamin and even they had tryptophan in them. I would definatly take it again. I also remember that there was some concern over how effective it was at controlling seratonin levels in the brain and the consensus at the time was that drug companies realized that due to the efficacy of tryptophan in treating depression they may not have been able to succesfully market paxil type drugs and so pressure was exerted on the FDA to implement the ban. The handfull of deaths didnt help either, but I recently read that 16 to 19 thousand people die each year due to reations from NSAIDs; and yet the FDA doesnt ban aspirin or motrin. I checked those two sites and the price is really high, prior to the ban a bottle of 100 tablets was about 5 bucks, but that was about the same for arginine, ala, alc and most of the other overpriced newly rediscovered "hot" supplements It really does work though.  I've also had good results from L-phenylalanine by itself and along with tyrosine. Earl Mindel's vitamin bible was full of good info about many amino acids that could be used for mood enhancement, dont know if its still in print(this was pre-WWW, in the early 80s)
6 feet 4in.tall, 270lbs, 17%b.f., almost 40; lifting since I was 10.
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 Excellent post , Stephen, you rinfo is right on. I ran a number of health food stores thru the 80's, and as I said earlier, the ban on tryp caused panic to the point of customers trying to talk me into selling it to them in the parking lot before it was to be sent back to the manufacturers. Prosac came onto the market just after the ban by a matter of months, so there you have it - you don't need CSI to figure this one out. I don't know however, where you were getting L-T for 5.00 for bottle of 100. I have here a distributer's product catalog that our stores used to order from, dated 1987, the 2 most popular brands we sold were Kal ( 14.99/60s) and Basics for Life (12.99/60s). The place I buy mine from now sells for 26.00/60s. Another reason I only use this source is because they are a drug/alcohol in-patient treatment center that uses supplements, meds, nutrtion, and 12 step program. Since this is the L-T that they use for their patients, used in a clinical enviroment, I trust it to be the best available.
RomanMVP
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 I don't believe there is any reason to prefer L-tryptophan over 5-HTP, which is easy to acquire.
David Tolson
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 I beg to differ on the issue of L-T vs. 5 htp. There's a huge amount of conflicting info with regards to 5 htp, from efficaciousness to safety. When it first came out some years back, I was ecstatic thinking it would do what L-T did. I didn't , and over the years, after recommending clients to try it, in reality, it never lived up to the hype. Now, a number of those clients have switched to L-T , and they'd be the first to tell you that the difference between the 2 are like night and day. And a few of these folks had been L-T users before the ban. These are the types of indiviuals who can tell the difference, regardless of "studies", pro and con. I've spoken first hand with clinicians who use L-T at their facilities on patients and they will tell you that , after trying 5 htp on patients when it first became available, it's effects were nothing like 5 htp. I asked one Doc who uses L-t in his practice why the FDA allows the sale of 5 htp in the mass market vs. L-T, he told me that since 5 htp is ineffective at best, it poses no threat to sales of SSRIs. For 5htp to work it needs a dopa decarboxylase inhibitor, the drug carbidopa, to prevent 5 htp from being converted into serotonin till it reaches the brain. The conversion has to take place in the brain, not before. 5 htp is converted into serotonin rapidly long before it reaches the brain. For anyone wanting to see the difference between the 2, try both. Start with 5htp for a month or two, then switch to L-tryptophan. Real life experiences are the only things that matter.
RomanMVP
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Guru

Group: Advanced Members
Posts: 4584
Member No.: 24436
Joined: 11-April 04

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 How would you compare this L-T cocktail to somthing say valium,or klonopin?
 Moderator @ Bodybuilding.net -Come check it out. [color=red][color=red]The things you own,end up owning you...Tyler Durden,Fight Club Those are my Abs in my avatar please respect! haha Valiums and [PLINK=2125]speed[/PLINK] but we don't do weed Steroids and alcohol, still a fuckin athlete Cock strong with my jock strap on with the time clock Bout to run the rock home Yo' ace boom coon in the hole in the clutch In the pocket on the field, without gettin touched!!!! -mystikal
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Advanced Member

Group: Advanced Members
Posts: 428
Member No.: 41194
Joined: 30-August 04

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 | QUOTE (shpongled @ Jan 26 2005, 05:23 PM) | | I don't believe there is any reason to prefer L-tryptophan over 5-HTP, which is easy to acquire. |
as in my knolege L-T is found in chocolamine. and 1kg/day of chocolamine has on the brain neurotransmiter the same effect as one canabis. canabis may be addictive. into my head there is the folowing statement : L-T turns into 5-HT or the 5-HT turn into L-T Since my childhood i was a nesquick/chocolats addict. i recently tried sertaline (SSRI) the first 50mg made me sleepy. and droped my Blood presure and heart rate. the 2nd shoot i just didnt felt the full effect. The 3rd 50mg shoot felt nothing and was able to stay awake. so i stoped 1month off later took back 50mg of sertaline HCL and felt nothings ! dispite the fact that every morning i daily use nesquick with cereals. sertaline has a limited effect on me. unless ur serotonine receptors are damaged natural black chocos and L-T can help are good  i get a better sleep paterns and memory after the sertaline use that lasted till now
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Guru

Group: Advanced Members
Posts: 4584
Member No.: 24436
Joined: 11-April 04

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 Thanks for the answer Roman...I didnt think you were whoring L-T BTW...I am greatful for the info that you have helped us with.
 Moderator @ Bodybuilding.net -Come check it out. [color=red][color=red]The things you own,end up owning you...Tyler Durden,Fight Club Those are my Abs in my avatar please respect! haha Valiums and [PLINK=2125]speed[/PLINK] but we don't do weed Steroids and alcohol, still a fuckin athlete Cock strong with my jock strap on with the time clock Bout to run the rock home Yo' ace boom coon in the hole in the clutch In the pocket on the field, without gettin touched!!!! -mystikal
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 | QUOTE (RomanMVP @ Jan 29 2005, 06:08 AM) | I beg to differ on the issue of L-T vs. 5 htp. There's a huge amount of conflicting info with regards to 5 htp, from efficaciousness to safety. When it first came out some years back, I was ecstatic thinking it would do what L-T did. I didn't , and over the years, after recommending clients to try it, in reality, it never lived up to the hype. Now, a number of those clients have switched to L-T , and they'd be the first to tell you that the difference between the 2 are like night and day. And a few of these folks had been L-T users before the ban. These are the types of indiviuals who can tell the difference, regardless of "studies", pro and con. I've spoken first hand with clinicians who use L-T at their facilities on patients and they will tell you that , after trying 5 htp on patients when it first became available, it's effects were nothing like 5 htp. I asked one Doc who uses L-t in his practice why the FDA allows the sale of 5 htp in the mass market vs. L-T, he told me that since 5 htp is ineffective at best, it poses no threat to sales of SSRIs. For 5htp to work it needs a dopa decarboxylase inhibitor, the drug carbidopa, to prevent 5 htp from being converted into serotonin till it reaches the brain. The conversion has to take place in the brain, not before. 5 htp is converted into serotonin rapidly long before it reaches the brain. For anyone wanting to see the difference between the 2, try both. Start with 5htp for a month or two, then switch to L-tryptophan. Real life experiences are the only things that matter. |
Well, I don't agree, but that's because my philosophy on how to best evaluate a supplement is entirely different. I don't think firsthand reports mean anything compared to double-blind, placebo-controlled studies. I can go out and find hundreds of firsthand reports from people who say that they drive better when they are drunk. You can even find a ton of doctors that will tell you that injectable steroids will give you liver cancer. Doesn't make it true, if there are no studies to back it up. What we know is that: -Dozens of studies have found that 5-HTP supplementation does increase serotonin levels in the brain. About 70% of an orally administered dose reaches the bloodstream. Given that it easily passes the BBB, if that amount reaches circulation you can bet that supplementation raises CNS levels, and there is a significant body of research out there that proves it. -Multiple clinical studies have shown that 5-HTP significantly decreases appetite and leads to weight loss. In contrast, there is little research on tryptophan in this arena. -There are also multiple double-blind, placebo-controlled trials indicating that 5-HTP is effective at decreasing depression. -Because 5-HTP will not compete with other neurotransmitter precursors for entry in to the brain, it will not decrease levels of dopamine, NE, etc. as tryptophan is known to do. For some, a decrease in dopamine levels is desirable, but for most, it is not. I have never seen evidence in the scientific literature that 5-HTP is unsafe. There is a lot of misinformation circulating on the internet, just as there is about every substance.
David Tolson
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 | QUOTE (Sir Charles Brown @ Jan 29 2005, 10:34 AM) | | QUOTE (RomanMVP @ Jan 29 2005, 09:08 AM) | | For 5htp to work it needs a dopa decarboxylase inhibitor, the drug carbidopa, to prevent 5 htp from being converted into serotonin till it reaches the brain. The conversion has to take place in the brain, not before. 5 htp is converted into serotonin rapidly long before it reaches the brain. |
That's exactly what I've been reading in the research I have done so far.
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Carbidopa helps but it is certainly not necessary. You all may want to check out this article: http://www.thorne.com/altmedrev/.fulltext/3/4/271.pdf
David Tolson
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 | QUOTE (RomanMVP @ Jan 25 2005, 07:39 AM) | | There's really no logical reason for tryptophan to lower one's gym experience (reduced contributions to the board because of tryptophan use ??!!). |
One of the most popular theories for why CNS fatigue occurs during exercise is that it is due to an increase in circulating tryptophan levels, and subsequently increased serotonin levels in the brain. It is pretty well-known that this can make you feel drowsy and fatigued.
David Tolson
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