I have developed VERY painful shoulders over that last year (unfortunately aggravated by two successful PH cycles). I am supplementing with
Glucosamine Sulfate and Aleve now, which help, but I beleive something which will work transdermally at the shoulder joint itself would be more effective (as I understand the bio-availability of GS is rather low).
My idea involves using one of the commercially available DMSO topicals consisting of 70% DMSO and 30%
Aloe Vera, and then adding some Glucosamine and Chondrotin (saturation not to exceed 100mg/ml. combinded). My questions are:
1) Will I smell of sulfur (breath and B.O.)? Will the addition of peppermint oil (etc) deal with it?
2) Will a 70% solution of DSMO carry 100mg/ml past the skin?? (From my understanding it will carry steamer trunks and other luggage if given the chance)

.
3) Should I dissolve the Glucosamine and Chondrotin in ISO first, or will it dissolve in the DSMO if I mix sufficiently?
3) If odor is unavoidable, would I be better off mixing
MSM, Glucosmine and Chondrotin into another transdermal carrier (i.e. is the MW of these compounds small enough?)
4) Should I try something like Aloe, Oleic acid, Isopropyl Palmitate and only a small amount of DSMO (like 5-10% of total volume of my carrier)?
Needless to say, my goals are not necessarily pain relief, but the overall improvement/betterment of the joint itself.
Thanks
Ronn